Koertge T E, Gunsolley J C, Domke T W, Nelson B J
Department of Periodontics, School of Dentistry, Virginia Commonwealth University, Richmond.
J Clin Dent. 1993;4(1):1-5.
An eight-week, double-blind, parallel and unsupervised clinical study was conducted to compare the ability of two dentifrices, Arm & Hammer Dental Care toothpaste and Crest toothpaste, to prevent the formation of stain induced by the twice daily use of 0.12% chlorhexidine gluconate (Peridex). Stain formation was evaluated through the use of a new index (Modified Stain Index) designed to selectively detect stain of the proximal and facial surfaces of the anterior teeth. Examinations of stain formation were conducted at two-week intervals for a total of eight weeks. The results indicated equivalent stain prevention benefits for Arm & Hammer Dental Care and Crest when evaluated during eight weeks of chlorhexidine therapy. The modified stain index was shown to be valuable for discriminating location and intensity of early stain formation.
进行了一项为期八周的双盲、平行且无监督的临床研究，以比较两种牙膏（爱茉莉牙膏和佳洁士牙膏）预防因每日两次使用0.12%葡萄糖酸氯己定（派丽奥）而导致色斑形成的能力。通过使用一种新的指数（改良色斑指数）来评估色斑形成情况，该指数旨在选择性地检测前牙近中面和唇面的色斑。色斑形成检查每隔两周进行一次，共持续八周。结果表明，在八周的氯己定治疗期间进行评估时，爱茉莉牙膏和佳洁士在预防色斑方面具有同等益处。改良色斑指数被证明对于区分早期色斑形成的位置和强度很有价值。
