Bollmer B W, Sturzenberger O P, Vick V, Grossman E
The Procter & Gamble Co., Cincinnati, Ohio, USA.
J Clin Dent. 1995;6(4):185-7.
Regular use of an effective oral rinse (0.12% chlorhexidine [CHX]) may be accompanied by tooth staining and slightly increased calculus formation. Since dentifrices containing soluble pyrophosphates are known to significantly reduce calculus formation, this study was designed to investigate whether CHX-induced staining and increased calculus may be reduced by the use of such dentifrices. The study compared stain and calculus formation in 163 subjects using a CHX oral rinse (Peridex, Procter & Gamble) according to label directions and either a pyrophosphate-containing anticalculus toothpaste (Tartar-Control Crest, 3.3% pyrophosphate) or an otherwise similar toothpaste without pyrophosphate (Regular Crest). Subjects were instructed to brush and floss ad lib and were examined after three and six months. Whole-mouth calculus occurrence was significantly reduced in the anticalculus toothpaste group at three and six months. Also, staining on the cosmetically important facial-anterior surfaces was significantly reduced at the 3-month examination. After six months the difference in facial anterior staining was still directionally favorable to the anticalculus toothpaste group but no longer statistically significant. These results indicate that routine brushing with an anticalculus toothpaste such as Tartar-Control Crest significantly reduces both facial-anterior staining and calculus occurrence in subjects using a CHX oral rinse. Whether more frequent or more thorough brushing would lead to still greater reductions remains to be investigated.
经常使用有效的口腔含漱液(0.12%氯己定[CHX])可能会伴有牙齿染色和牙结石形成略有增加。由于已知含可溶性焦磷酸盐的牙膏可显著减少牙结石形成,本研究旨在调查使用此类牙膏是否可减少CHX引起的染色和牙结石增加。该研究比较了163名受试者按照标签说明使用CHX口腔含漱液(Peridex,宝洁公司),并使用含焦磷酸盐的防牙结石牙膏(佳洁士防结石牙膏,3.3%焦磷酸盐)或不含焦磷酸盐的类似牙膏(普通佳洁士牙膏)后的染色和牙结石形成情况。受试者被指示随意刷牙和使用牙线,并在3个月和6个月后进行检查。防牙结石牙膏组在3个月和6个月时全口牙结石的发生率显著降低。此外,在3个月检查时,在美观重要的面部前牙表面的染色也显著减少。6个月后,面部前牙染色的差异在方向上仍有利于防牙结石牙膏组,但不再具有统计学意义。这些结果表明,使用防牙结石牙膏(如佳洁士防结石牙膏)进行常规刷牙可显著减少使用CHX口腔含漱液的受试者的面部前牙染色和牙结石发生率。更频繁或更彻底的刷牙是否会导致更大程度的减少仍有待研究。