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骆驼红细胞中与容量相关的钾转运

Volume-dependent potassium transport in camel red blood cells.

作者信息

Gharaibeh N S, Rawashdeh N M

机构信息

Department of Physiology and Biochemistry, Jordan University of Science and Technology, Irbid.

出版信息

Membr Biochem. 1993 Apr-Jun;10(2):99-106. doi: 10.3109/09687689309150257.

DOI:10.3109/09687689309150257
PMID:8395642
Abstract

In this study the volume-dependent, ouabain-resistant K+ influx and efflux in camel red blood cells were measured with the tracer 86Rb+. The results showed that the camel erythrocytes do not have the Na(+)-K+ cotransport. The cell swelling increases a ouabain-resistant K+ influx and shrinkage decreases it nearly two-fold. The swelling-stimulated K+ influx and efflux were chloride dependent. The anion dependence of K+ influx in swollen cells was as follows: Br- > Cl- > NO3. The pH-dependent curve for swelling-stimulated potassium influx, and the active K+ influx in camel erythrocytes were determined. The findings indicate that camel erythrocytes' potassium transport system has many similarities to other mammalian species.

摘要

在本研究中,用示踪剂86Rb+测量了骆驼红细胞中体积依赖性、哇巴因抗性的钾离子流入和流出。结果表明,骆驼红细胞不存在钠钾协同转运。细胞肿胀会增加哇巴因抗性的钾离子流入,而细胞收缩会使其减少近两倍。肿胀刺激的钾离子流入和流出依赖于氯离子。肿胀细胞中钾离子流入的阴离子依赖性如下:Br->Cl->NO3。测定了肿胀刺激的钾离子流入的pH依赖性曲线以及骆驼红细胞中的活性钾离子流入。这些发现表明,骆驼红细胞的钾离子转运系统与其他哺乳动物物种有许多相似之处。

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