Kochev D M, Vorisova R S, Zabolotskiĭ D A, Miagkova G I
Bioorg Khim. 1993 Jun;19(6):597-611.
The review covers the aspects of classification, specificity and structure--biological activity relations in leukotriene receptor antagonists which blockade the action of the acyclic arachidonate metabolites. Prospects of designing new medicines based on these compounds are also discussed.
该综述涵盖了白三烯受体拮抗剂的分类、特异性以及结构与生物活性关系等方面,这些拮抗剂可阻断无环花生四烯酸代谢产物的作用。文中还讨论了基于这些化合物设计新药的前景。