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Primary structure of the mouse beta 1-adrenergic receptor gene.

作者信息

Jasper J R, Link R E, Chruscinski A J, Kobilka B K, Bernstein D

机构信息

Department of Pediatrics, Stanford University, CA 94305.

出版信息

Biochim Biophys Acta. 1993 Sep 13;1178(3):307-9. doi: 10.1016/0167-4889(93)90209-8.

DOI:10.1016/0167-4889(93)90209-8
PMID:8395893
Abstract

The mouse beta 1-adrenergic receptor was isolated from a genomic library and cloned into pBluescript SK-. Characterization of the clone revealed an open reading frame which encodes a predicted protein of 466 amino acids. The mouse beta 1 receptor is 92.7% identical to the human sequence, 98.5% identical to the rat sequence, and contains a consensus site for N-linked glycosylation at Asn-15 and a cAMP-dependent protein kinase phosphorylation site at Ser-301.

摘要

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