Fujimoto J, Okamoto E, Yamanaka N, Oriyama T, Furukawa K, Kawamura E, Tanaka T, Tomoda F
First Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan.
Arch Surg. 1993 Sep;128(9):1065-9. doi: 10.1001/archsurg.1993.01420210129021.
Although autotransfusion is used in a wide variety of surgical procedures, it is largely unexplored for use in oncologic operations. This study evaluates the impact of autotransfusion in hepatectomy for hepatocellular carcinoma.
Fifty-four patients with hepatocellular carcinoma underwent hepatectomy by receiving autologous blood transfusion (group 1). Fifty patients receiving homologous blood without any autologous blood were matched for comparison (group 2).
No statistical differences were found between group 1 and group 2 patients in cumulative recurrence rates (62.8% vs 67.3%, respectively) or cumulative survival rates (61.9% vs 52.8%). Autologous transfusion reduced the mean volume of homologous blood used (814 mL vs 3466 mL). The mean postoperative hemoglobin level, platelet count, prothrombin time, and partial thromboplastin time were comparable between groups.
Autotransfusion is a safe and effective procedure in patients with hepatocellular carcinoma undergoing hepatectomy.
尽管自体输血在多种外科手术中都有应用，但在肿瘤手术中的应用在很大程度上尚未得到充分探索。本研究评估了自体输血在肝细胞癌肝切除术中的影响。
54例肝细胞癌患者接受肝切除术并进行自体输血（第1组）。50例接受异体输血且未进行任何自体输血的患者作为对照（第2组）。
第1组和第2组患者在累积复发率（分别为62.8%和67.3%）或累积生存率（分别为61.9%和52.8%）方面未发现统计学差异。自体输血减少了异体血的平均使用量（814毫升对3466毫升）。两组患者术后平均血红蛋白水平、血小板计数、凝血酶原时间和部分凝血活酶时间相当。
自体输血对于接受肝切除术的肝细胞癌患者是一种安全有效的方法。
