Vergara E, Lastoria S, Varrella P, Lapenta L, Salvatore M
Department of Nuclear Medicine, Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy.
J Nucl Biol Med (1991). 1993 Jun;37(2):65-8.
In a patient with metastatic Hurthle cell carcinoma of the thyroid, a subgroup of follicular carcinoma, scintigraphy with pentavalent 99mTc-labeled dimercaptosuccinic acid (V)DMSA showed a significant uptake of the radiopharmaceutical in all tumor sites. We suggest that the accumulation of 99mTc-(V)DMSA within metastases of Hurthle cell thyroid tumor may have a useful role in the staging of these patients, especially when radioiodine fails to concentrate.
在一名患有转移性甲状腺嗜酸性细胞癌(滤泡癌的一个亚组)的患者中,用五价99mTc标记的二巯基丁二酸(V)DMSA进行闪烁扫描显示,放射性药物在所有肿瘤部位均有明显摄取。我们认为,99mTc-(V)DMSA在甲状腺嗜酸性细胞瘤转移灶中的蓄积可能在这些患者的分期中具有重要作用,尤其是在放射性碘不能浓聚时。