Suleĭmanova N S, Skurnik A R, Donnikov A E, Sukhikh G T
Biull Eksp Biol Med. 1993 Jun;115(6):637-8.
The effect of cytomegalovirus infection (CMVI) on the phagocytic activity of leukocytes was studied in patients by the method of luminol-dependent chemiluminescence (CL) used to evaluate the production of oxygen radicals by the peripheral blood neutrophils in phagocytosis of opsonized zymosan (OZ) in 10 female patients with active CMVI and 10 women of the control group. In the patients with CMVI, chemiluminescence in OZ phagocytosis was found to be reduced nearly by 1.5-fold as compared with the controls (pt < 0.05).
采用鲁米诺依赖性化学发光法(CL),对10例活动性巨细胞病毒感染(CMVI)女性患者和10例对照组女性进行研究,以评估外周血中性粒细胞在吞噬调理酵母聚糖(OZ)过程中氧自由基的产生情况,从而探讨CMVI对白细胞吞噬活性的影响。结果发现,与对照组相比,CMVI患者吞噬OZ时的化学发光降低了近1.5倍(pt<0.05)。