肾母细胞瘤中的（7；7）（p13；q21）易位

Translocation (7;7)(p13;q21) in a Wilms' tumor.

作者信息

Sawyer J R, Winkel E W, Redman J F, Roloson G J

机构信息

Department of Pathology, University of Arkansas for Medical Sciences, Little Rock.

出版信息

Cancer Genet Cytogenet. 1993 Aug;69(1):57-9. doi: 10.1016/0165-4608(93)90114-2.

DOI:10.1016/0165-4608(93)90114-2

PMID:8397065

Abstract

Reports of single chromosome aberrations in Wilms' tumors are rare, with most tumors being characterized by multiple complex karyotype aberrations. An 11-month-old female patient with Wilms' tumor and a derivative chromosome 7 resulting from t(7;7)(p13;q21) as the sole cytogenetic aberration is described.

摘要

肾母细胞瘤中单一染色体畸变的报道很少见，大多数肿瘤的特征是具有多个复杂的核型畸变。本文描述了一名11个月大的患有肾母细胞瘤的女性患者，其唯一的细胞遗传学畸变是由t(7;7)(p13;q21)产生的衍生染色体7。