Belova E V
Kardiologiia. 1993;33(3):37-9.
The study was undertaken to examine 30 healthy males and 67 patients with arterial hypertension. The author studied urinary excretion of 17-KS and blood levels of cortisol and adrenocorticotropic hormone before and after emotional stress induced by the "hour/compass" test. It was found that due to the stress, the release of the metabolites corticosteroids was higher in intensity than changes in blood concentrations of cortisol and adrenocorticotropic hormone in borderline hypertension and Stage I hypertensive disease, whereas these parameters were in an inverse ratio in Stage II hypertensive disease. Such changes occurred in patients with secondary hypertension. The ratio should be used as a diagnostic test.
该研究旨在检查30名健康男性和67名动脉高血压患者。作者研究了在“时钟/罗盘”测试诱发情绪应激前后,17-酮类固醇的尿排泄量以及皮质醇和促肾上腺皮质激素的血浓度。结果发现,由于应激,在临界高血压和I期高血压病中,皮质类固醇代谢产物的释放强度高于皮质醇和促肾上腺皮质激素血浓度的变化,而在II期高血压病中这些参数呈反比。继发性高血压患者也出现了这种变化。该比值应用作诊断试验。