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利巴韦林气雾剂:减少员工接触的方法。

Ribavirin aerosol: methods for reducing employee exposure.

作者信息

Arnold S D, Alonso R

出版信息

AAOHN J. 1993 Aug;41(8):382-92.

PMID:8397555
Abstract
  1. Two new exhaust control methods for scavenging and removing excess ribavirin aerosol were evaluated. Air samples were collected from pediatric intensive care rooms to determine the concentration of ribavirin. 2. Both control methods produced a 99.9% reduction between patient breathing zone concentrations and general room air concentrations. The average room air concentrations of ribavirin were 64 and 37 micrograms/m3 with the control methods in place, compared to average patient breathing zone concentrations of 45,000 and 58,000 micrograms/m3. 3. Additional control methods are reviewed, and published ribavirin environmental monitoring data is summarized. 4. Though the effect on fetal development in humans is not known, it is recommended that occupational exposure to ribavirin aerosol be minimized. A safe level for occupational exposure was calculated to be 91 micrograms/m3 for an 8-hour time weighted average.
摘要
  1. 评估了两种用于清除和去除过量利巴韦林气雾剂的新排气控制方法。从儿科重症监护病房采集空气样本以测定利巴韦林的浓度。2. 两种控制方法均使患者呼吸区域浓度与病房一般空气浓度之间降低了99.9%。在采用控制方法的情况下,利巴韦林的病房平均空气浓度分别为64和37微克/立方米,而患者呼吸区域的平均浓度分别为45,000和58,000微克/立方米。3. 审查了其他控制方法,并总结了已发表的利巴韦林环境监测数据。4. 虽然利巴韦林对人类胎儿发育的影响尚不清楚,但建议尽量减少职业性接触利巴韦林气雾剂。经计算,职业接触的安全水平为8小时时间加权平均91微克/立方米。

相似文献

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Ribavirin aerosol: methods for reducing employee exposure.利巴韦林气雾剂:减少员工接触的方法。
AAOHN J. 1993 Aug;41(8):382-92.
2
Evaluation of a double-enclosure double-vacuum unit scavenging system for ribavirin administration.用于利巴韦林给药的双罩双真空单元清除系统的评估。
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Occupational exposures to aerosolized pharmaceuticals and control strategies.
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Occupational exposure to nitrous oxide - the role of scavenging and ventilation systems in reducing the exposure level in operating rooms.职业性接触氧化亚氮——清除和通风系统在降低手术室接触水平中的作用。
Int J Hyg Environ Health. 2007 Mar;210(2):133-8. doi: 10.1016/j.ijheh.2006.07.004. Epub 2006 Oct 10.
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Use of an in-house-built ribavirin aerosol evacuation system to control incidental employee exposure to ribavirin aerosol.使用内部构建的利巴韦林气雾剂排放系统来控制员工意外接触利巴韦林气雾剂。
J Clin Eng. 1996 Jan-Feb;21(1):46-50. doi: 10.1097/00004669-199601000-00014.
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Reduced environmental exposure to aerosolized ribavirin using a simple containment system.使用简单的隔离系统减少环境中雾化利巴韦林的暴露。
Pediatr Infect Dis J. 1991 Mar;10(3):217-21. doi: 10.1097/00006454-199103000-00010.
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[Environmental and biological control in a population exposed to isoflurane in the operating room].[手术室中暴露于异氟烷的人群的环境与生物控制]
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Exposure to metalworking fluid aerosols and determinants of exposure.接触金属加工液气雾剂及接触的决定因素。
Ann Occup Hyg. 2008 Oct;52(7):597-605. doi: 10.1093/annhyg/men043. Epub 2008 Jul 29.
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Assessing exposures of health-care personnel to aerosols of ribavirin--California.评估加利福尼亚州医护人员对利巴韦林气雾剂的暴露情况。
MMWR Morb Mortal Wkly Rep. 1988 Sep 16;37(36):560-3.

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