Gómez-Ferrer F, Antón V, Llombart A
Catedrático de Cirugía, Universidad de Valencia.
Rev Esp Enferm Dig. 1993 Aug;84(2):85-9.
A study was made to compare nerve regeneration of the anterior gastric wall following either seromyotomy or gastrotomy with eversion suturing; both approaches extending from the antrum to the fundus. Twenty-eight preadult Wistar rats were divided into three groups: Group I (control: sham operated animals; n = 8); Group II (seromyotomy with posterior truncal vagotomy; n = 10); and Group III (gastrotomy with posterior truncal vagotomy; n = 10). Nerve regeneration was evaluated immunohistochemically two months after the operation. Groups II and III presented gastric dilatation postmortem. Both groups showed complete denervation of the anterior gastric wall, with no vagal fibers crossing the section line. Amputation neuromas and Schwann cells were commonly observed. In conclusion, both seromyotomy and gastrotomy are efficient methods for denervating the anterior gastric wall.
进行了一项研究，比较胃前壁在浆膜肌层切开术或胃切开术并外翻缝合后的神经再生情况；两种方法均从胃窦延伸至胃底。28只未成年Wistar大鼠被分为三组：第一组（对照组：假手术动物；n = 8）；第二组（浆膜肌层切开术加迷走神经干后切断术；n = 10）；第三组（胃切开术加迷走神经干后切断术；n = 10）。术后两个月通过免疫组织化学评估神经再生情况。第二组和第三组在死后出现胃扩张。两组均显示胃前壁完全去神经支配，无迷走神经纤维穿过切面线。常见截肢性神经瘤和施万细胞。总之，浆膜肌层切开术和胃切开术都是使胃前壁去神经支配的有效方法。
