• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

MAP kinases: activation, subcellular localization and role in the control of cell proliferation.

作者信息

Lenormand P, Pagès G, Sardet C, L'Allemain G, Meloche S, Pouysségur J

机构信息

Centre de Biochimie-CNRS, Université de Nice, France.

出版信息

Adv Second Messenger Phosphoprotein Res. 1993;28:237-44.

PMID:8398409
Abstract
摘要

相似文献

1
MAP kinases: activation, subcellular localization and role in the control of cell proliferation.
Adv Second Messenger Phosphoprotein Res. 1993;28:237-44.
2
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry.生长因子诱导的基因表达和细胞周期进入需要p42/p44丝裂原活化蛋白激酶的核转位。
EMBO J. 1999 Feb 1;18(3):664-74. doi: 10.1093/emboj/18.3.664.
3
Thrombopoietin induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in a human thrombopoietin-dependent cell line.血小板生成素在人血小板生成素依赖细胞系中诱导丝裂原活化蛋白激酶的酪氨酸磷酸化并激活该激酶。
Biochem Biophys Res Commun. 1995 Dec 5;217(1):230-7. doi: 10.1006/bbrc.1995.2768.
4
Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase.丝裂原活化蛋白激酶与丝裂原活化蛋白激酶激酶的相互作用：其在调控丝裂原活化蛋白激酶核质转运中的可能作用。
EMBO J. 1997 Apr 15;16(8):1901-8. doi: 10.1093/emboj/16.8.1901.
5
Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors.人类肿瘤中41/43千道尔顿丝裂原活化蛋白激酶信号通路的组成性激活。
Oncogene. 1999 Jan 21;18(3):813-22. doi: 10.1038/sj.onc.1202367.
6
Rapid activation of mitogen-activated protein kinase and p21ras by prolactin and interleukin 2 in rat Nb2 node lymphoma cells.催乳素和白细胞介素2在大鼠Nb2淋巴结淋巴瘤细胞中对丝裂原活化蛋白激酶和p21ras的快速激活作用
Cell Growth Differ. 1995 Oct;6(10):1235-44.
7
An anchorage-dependent signal distinct from p42/44 MAP kinase activation is required for cell cycle progression.细胞周期进程需要一种不同于p42/44丝裂原活化蛋白激酶激活的锚定依赖性信号。
Oncogene. 1998 Sep 10;17(10):1271-7. doi: 10.1038/sj.onc.1202057.
8
Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation.通过与p38丝裂原活化蛋白（MAP）激酶结合实现丝裂原活化蛋白激酶磷酸酶-1的催化激活：p38 C末端结构域在其负调控中的关键作用。
Biochem J. 2000 Nov 15;352 Pt 1(Pt 1):155-63.
9
MAP kinase activation during heat shock in quiescent and exponentially growing mammalian cells.静止期和指数生长期哺乳动物细胞热休克期间的丝裂原活化蛋白激酶激活
FEBS Lett. 1993 Jun 14;324(2):191-5. doi: 10.1016/0014-5793(93)81391-c.
10
Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation.丝裂原活化蛋白激酶ERK2的磷酸化促进其同二聚化和核转位。
Cell. 1998 May 15;93(4):605-15. doi: 10.1016/s0092-8674(00)81189-7.

引用本文的文献

1
Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells.细胞外信号调节激酶磷酸化在酪氨酸和苏氨酸的亚细胞分布依赖于氧化还原状态在鼠肺细胞。
PLoS One. 2018 Feb 28;13(2):e0193022. doi: 10.1371/journal.pone.0193022. eCollection 2018.
2
Dexmedetomidine inhibits tumor necrosis factor-alpha and interleukin 6 in lipopolysaccharide-stimulated astrocytes by suppression of c-Jun N-terminal kinases.右美托咪定通过抑制c-Jun氨基末端激酶来抑制脂多糖刺激的星形胶质细胞中的肿瘤坏死因子-α和白细胞介素6。
Inflammation. 2014 Jun;37(3):942-9. doi: 10.1007/s10753-014-9814-4.
3
Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases.
双重特异性磷酸酶 10 和 16 是 EGF 刺激的 ERK 活性的正调节剂：JNK/p38 选择性 MAPK 磷酸酶对 ERK 信号的间接调节。
Cell Signal. 2012 May;24(5):1002-11. doi: 10.1016/j.cellsig.2011.12.021. Epub 2012 Jan 3.
4
Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest.GPR30 的激活通过持续激活 Erk1/2、c-jun/c-fos 依赖性上调 p21 以及诱导 G2 细胞周期阻滞来抑制前列腺癌细胞的生长。
Cell Death Differ. 2010 Sep;17(9):1511-23. doi: 10.1038/cdd.2010.20. Epub 2010 Mar 5.
5
Genomic priming of the antisecretory response to estrogen in rat distal colon throughout the estrous cycle.在整个发情周期中，大鼠远端结肠对雌激素的抗分泌反应的基因组启动。
Mol Endocrinol. 2009 Nov;23(11):1885-99. doi: 10.1210/me.2008-0248. Epub 2009 Oct 21.
6
The stimulus-dependent co-localization of serum- and glucocorticoid-regulated protein kinase (Sgk) and Erk/MAPK in mammary tumor cells involves the mutual interaction with the importin-alpha nuclear import protein.血清和糖皮质激素调节蛋白激酶（Sgk）与细胞外信号调节激酶/丝裂原活化蛋白激酶（Erk/MAPK）在乳腺肿瘤细胞中依赖刺激的共定位涉及与输入蛋白α核输入蛋白的相互作用。
Exp Cell Res. 2007 Sep 10;313(15):3261-75. doi: 10.1016/j.yexcr.2007.07.009. Epub 2007 Jul 19.
7
The effects of a novel MEK inhibitor PD184161 on MEK-ERK signaling and growth in human liver cancer.新型MEK抑制剂PD184161对人肝癌中MEK-ERK信号传导及生长的影响
Neoplasia. 2006 Jan;8(1):1-8. doi: 10.1593/neo.05373.
8
Distinct requirements for the Sprouty domain for functional activity of Spred proteins.Sprouty结构域对Spred蛋白功能活性的不同要求。
Biochem J. 2005 Jun 1;388(Pt 2):445-54. doi: 10.1042/BJ20041284.
9
Transforming growth factor beta 1 inhibits mitogen-activated protein kinase induced by basic fibroblast growth factor in smooth muscle cells.转化生长因子β1抑制碱性成纤维细胞生长因子在平滑肌细胞中诱导的丝裂原活化蛋白激酶。
Biochem J. 1996 May 15;316 ( Pt 1)(Pt 1):167-73. doi: 10.1042/bj3160167.
10
Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1).哺乳动物丝裂原活化蛋白激酶激酶（MEK1）的组成型突变体和假定的调节性丝氨酸磷酸化位点。
EMBO J. 1994 Jul 1;13(13):3003-10. doi: 10.1002/j.1460-2075.1994.tb06599.x.