Rosenberg C R
Institute of Environmental Medicine, New York University Medical Center, NY 10010.
Br J Ind Med. 1993 Sep;50(9):822-6. doi: 10.1136/oem.50.9.822.
An investigation was conducted to examine the reliability (reproducibility) of self reported occupational histories obtained from a cohort of 326 capacitor manufacturing workers who had participated in an epidemiological study relating health abnormalities to exposure to polychlorinated biphenyls (PCBs). For a subsample of the cohort (n = 164) in which occupational histories were obtained twice (in 1976 and 1979), reliability of cumulative exposure to PCBs ranged from 93.6% for the early PCB period (1947-70) to 95.7% for the late PCB period (1971-6). These respective reliabilities were lower, however, for workers who changed jobs often. Workers above the median value of a weighted job change index had early and late reliabilities of 89.9% and 83.6% respectively. Reliability is a relevant factor when calculating power or sample size during the planning stage of epidemiological studies, for interpretation or adjustment of estimates in the analysis stage, or for determination of study feasibility.
对一组326名参与了一项将健康异常与多氯联苯(PCB)暴露相关联的流行病学研究的电容器制造工人进行了调查,以检验自我报告的职业史的可靠性(可重复性)。对于该队列中的一个子样本(n = 164),其职业史被获取了两次(分别在1976年和1979年),PCB累积暴露的可靠性在早期PCB时期(1947 - 1970年)为93.6%,在晚期PCB时期(1971 - 1976年)为95.7%。然而,对于频繁更换工作的工人,这些各自的可靠性较低。加权工作变更指数高于中位数的工人,早期和晚期的可靠性分别为89.9%和83.6%。在流行病学研究的规划阶段计算功效或样本量时,在分析阶段解释或调整估计值时,或确定研究可行性时,可靠性都是一个相关因素。