Degonda M, Wyss M, Angst J
Psychiatric University Hospital Zurich, Research Department, Switzerland.
Eur Arch Psychiatry Clin Neurosci. 1993;243(1):16-22. doi: 10.1007/BF02191519.
The cross-sectional and longitudinal association between obsessive-compulsive syndrome (OCS) and other psychiatric problems and the course over 11 years was examined in a Swiss cohort of young adults. As the prevalence of obsessive-compulsive disorders, defined according to the DSM-III was very low (n = 5), we applied a lower diagnostic threshold based on obsessive-compulsive symptoms and social impairment, to define an OCS. The weighted lifetime prevalence rate for OCS at age 30 years was 5.5%. The mean age of onset was 17.1 +/- 4.9 years for males, and 19.1 +/- 5.1 year for females. OCS was associated with all subtypes of depressive disorders as well as with social phobia and agoraphobia. Although the longitudinal analysis showed no stability at the diagnostical level, there was some stability on the symptom level. Perhaps subjects with OCS learned in time to cope and to live with their symptoms without suffering.
在瑞士一组年轻成年人队列中，研究了强迫综合征（OCS）与其他精神问题之间的横断面和纵向关联以及11年的病程。由于根据《精神疾病诊断与统计手册第三版》（DSM-III）定义的强迫症患病率非常低（n = 5），我们基于强迫症状和社会功能损害应用了较低的诊断阈值来定义OCS。30岁时OCS的加权终生患病率为5.5%。男性的平均发病年龄为17.1±4.9岁，女性为19.1±5.1岁。OCS与所有类型的抑郁症以及社交恐惧症和广场恐惧症相关。尽管纵向分析显示在诊断层面上没有稳定性，但在症状层面上存在一定稳定性。也许患有OCS的受试者及时学会了应对并与症状共处而不痛苦。
