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梅尼埃病的手术指征。

Indications for surgery in Mé Niére's disease.

作者信息

Pulec J L

出版信息

Laryngoscope. 1977 Apr;87(4 Pt 1):542-56.

PMID:839942
Abstract

Ménière's disease has been shown to have multiple causes, each of which requires a specific treatment. Patients who do not respond to medical treatment often are allowed to suffer prolonged disability from their symptoms or develop permanent hearing loss without the benefit of surgery. The physician's uncertainty regarding which patient will ultimately respond to medical treatment or have spontaneous remission of symptoms can cause a delay in what would otherwise have been definitive surgical treatment which would have allowed the patient to return to a happy and productive life. A careful analysis of 120 patients studied intensively for five years has shown that patients who exhibit specific characteristics and diagnostic findings will ultimately require surgery for control and relief of their symptoms, while others can be expected to recover with medical treatment. Fifty-six of the 120 patients ultimately required surgery to rid them of their symptoms. These patients were almost exclusively of the group considered to be idiopathic, viral, small internal auditory canal syndrome, or caused by physical or acoustic trauma. Those patients who had other causes for their Ménère's disease rarely required surgical treatment and were well controlled by specific medical therapy. These observations would seem to provide us with information which would allow patients who might be reasonably stages of their disease where conservative measures can more often be expected to give complete relief with preservation of hearing. The indications for surgery in patients with Ménière's disease based on this information will be reviewed. The use of this knowledge has significantly reduced the morbiditiy associated with Ménière's disease.

摘要

梅尼埃病已被证实有多种病因,每种病因都需要特定的治疗方法。对药物治疗无反应的患者常常因症状而长期致残,或者在未受益于手术的情况下出现永久性听力损失。医生对于哪些患者最终会对药物治疗有反应或症状会自发缓解存在不确定性,这可能会导致原本可以进行的确定性手术治疗延迟,而这种手术治疗本可使患者恢复幸福而有意义的生活。对120名患者进行了为期五年的深入研究,结果表明,表现出特定特征和诊断结果的患者最终需要手术来控制和缓解症状,而其他患者有望通过药物治疗康复。120名患者中有56名最终需要手术来消除症状。这些患者几乎全属于被认为是特发性、病毒性、内耳道狭小综合征或由物理或声学创伤引起的类别。那些因其他原因患有梅尼埃病的患者很少需要手术治疗,通过特定的药物治疗就能得到很好的控制。这些观察结果似乎为我们提供了信息,使我们能够在疾病的合理阶段告知患者,在这些阶段,保守措施通常更有可能在保留听力的情况下完全缓解症状。基于这些信息,将对梅尼埃病患者的手术指征进行综述。运用这些知识已显著降低了与梅尼埃病相关的发病率。

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