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1988年至1991年卢旺达基加利性病患者中的艾滋病毒感染情况

HIV infection among STD patients--Kigali, Rwanda, 1988 to 1991.

作者信息

Karita E, Martinez W, Van de Perre P, Nziyumvira A, Nyiraminani J, Butera J B, Fox E

机构信息

Rwanda National AIDS Control Program, Ministry of Health, Kigali, Rwanda.

出版信息

Int J STD AIDS. 1993 Jul-Aug;4(4):211-3. doi: 10.1177/095646249300400406.

DOI:10.1177/095646249300400406
PMID:8399500
Abstract

To follow the progression of HIV seropositivity among heterosexual adults at risk for HIV infection in the country of Rwanda prospectively, up to 100 patients with sexually transmitted diseases (STD) were tested each month from 1988 to 1991 at the health centre of Biryogo, which is located in a very crowded sector of the capital city, Kigali. Each patient had a blood sample tested anonymously for the presence of HIV antibodies. HIV seropositivity was defined as a reactive ELISA test combined to a reactive Western blot test. The overall HIV seropositivity among the 2058 subjects tested was 61%. It was higher (73%) among the 688 women tested as compared to the 1362 men tested (55%; P < 0.001). The per cent HIV seropositivity did not increase between 1988 and 1991, neither among the male nor among the female clinic attenders. However, the per cent seropositivity was higher in the older age groups, especially among the males. This exceedingly high proportion of HIV-infected STD patients in Kigali re-emphasizes the urgent need to include STD treatment, prevention and control among the priority actions for decreasing HIV transmission in African towns. Also, as the per cent seropositivities did not show any trend to increase over the 4-year period considered, we propose that our intensive HIV serosurveillance strategy among STD patients in Kigali be modified, since the plateau of HIV infection appears to have been attained in this particular high-risk population.

摘要

为前瞻性地追踪卢旺达国内有感染艾滋病毒风险的异性恋成年人群中艾滋病毒血清阳性的进展情况,1988年至1991年期间,每月在位于首都基加利一个非常拥挤地区的比里约戈健康中心对多达100名性传播疾病(STD)患者进行检测。每位患者的血样都进行匿名检测,以确定是否存在艾滋病毒抗体。艾滋病毒血清阳性定义为酶联免疫吸附测定(ELISA)试验呈阳性且蛋白免疫印迹试验(Western blot)呈阳性。在接受检测的2058名受试者中,总体艾滋病毒血清阳性率为61%。在接受检测的688名女性中,这一比例较高(73%),而在接受检测的1362名男性中,该比例为55%(P<0.001)。1988年至1991年期间,男性和女性门诊患者中的艾滋病毒血清阳性率均未增加。然而,老年组的血清阳性率较高,尤其是男性。基加利感染艾滋病毒的性传播疾病患者比例极高,再次强调迫切需要将性传播疾病的治疗、预防和控制纳入非洲城镇减少艾滋病毒传播的优先行动之中。此外,由于在所考虑的4年期间血清阳性率没有任何上升趋势,我们建议修改我们在基加利对性传播疾病患者进行的密集艾滋病毒血清监测策略,因为在这一特定的高风险人群中似乎已达到艾滋病毒感染的平稳期。

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