Characteristics of peripheral and peritoneal lymphocytes from continuous ambulatory peritoneal dialysis patients.

The role of peritoneal lymphocytes in host immunity for continuous ambulatory peritoneal dialysis (CAPD) patients is just beginning to be understood. CAPD therapy increases the proportion of peritoneal lymphocytes, most of which demonstrate signs of activation. There are decreased peritoneal T cells and increased peritoneal B cells as compared to the patients' peripheral blood. When studies examine immunophenotypes of peripheral and peritoneal lymphocytes over time, no significant changes are found. Although changes in peritoneal lymphocyte subsets occur during peritonitis episodes, there are no changes in peripheral blood lymphocytes. The purpose of this article is to provide a brief review of research that has studied lymphocytes in CAPD patients.