Lewis S L, Kutvirt S G, Cooper C L, Bonner P N, Holmes C J
Department of Pathology, University of New Mexico, Albuquerque 87131.
Perit Dial Int. 1993;13 Suppl 2:S273-7.
The role of peritoneal lymphocytes in host immunity for continuous ambulatory peritoneal dialysis (CAPD) patients is just beginning to be understood. CAPD therapy increases the proportion of peritoneal lymphocytes, most of which demonstrate signs of activation. There are decreased peritoneal T cells and increased peritoneal B cells as compared to the patients' peripheral blood. When studies examine immunophenotypes of peripheral and peritoneal lymphocytes over time, no significant changes are found. Although changes in peritoneal lymphocyte subsets occur during peritonitis episodes, there are no changes in peripheral blood lymphocytes. The purpose of this article is to provide a brief review of research that has studied lymphocytes in CAPD patients.
腹膜淋巴细胞在持续性非卧床腹膜透析（CAPD）患者宿主免疫中的作用才刚刚开始被了解。CAPD治疗会增加腹膜淋巴细胞的比例，其中大多数表现出活化迹象。与患者外周血相比，腹膜T细胞减少而腹膜B细胞增加。当研究随时间检查外周血和腹膜淋巴细胞的免疫表型时，未发现显著变化。尽管在腹膜炎发作期间腹膜淋巴细胞亚群会发生变化，但外周血淋巴细胞没有变化。本文的目的是简要回顾一下针对CAPD患者淋巴细胞的研究。
