Kahán Z, Szücs M, Vecsernyés M, Eckhardt S
Albert Szent-György Medical University, Department of Radiology, Hungary.
Breast Cancer Res Treat. 1993;26(1):41-7. doi: 10.1007/BF00682698.
Ligands binding to epidermal growth factor-receptors (EGF-Rs) as epidermal growth factor-like activity (EGF-like activity), along with EGF-R levels, were determined from human primary breast cancer samples. Receptor analysis revealed a single class of high affinity binding sites. Ng/mg protein EGF-like activity quantities were measured in cytosols, and were inversely correlated with EGF-R contents (p < 0.01), estimated by two-point assays.
从人原发性乳腺癌样本中测定了与表皮生长因子受体（EGF-Rs）结合的具有表皮生长因子样活性（EGF样活性）的配体以及EGF-R水平。受体分析显示存在一类高亲和力结合位点。通过两点分析法估计，在细胞溶质中测量了每毫克蛋白质的EGF样活性量，其与EGF-R含量呈负相关（p < 0.01）。
