Gilbey M P, Spyer K M
Royal Free Hospital School of Medicine, London, UK.
Curr Opin Neurol Neurosurg. 1993 Aug;6(4):518-23.
Investigations continue into the central neuronal circuitry involved in cardiovascular control, the activity of sympathetic efferents, cardiovascular responses, and experimental hypertension. Neurons within the ventrolateral medulla are integral to several reflex pathways. The activation of neurons within the A5 cell group can generate complex patterns of sympathetic and cardiovascular response. The type of respiratory modulation of a sympathetic neuron may be associated with its function. Opioid mechanisms within the central nervous system are important in cardiovascular responses to hemorrhage. The central actions of angiotensin II and atrial natriuretic peptide may blunt the baroreceptor reflex in spontaneously hypertensive rats.
对参与心血管控制的中枢神经回路、交感传出神经活动、心血管反应及实验性高血压的研究仍在继续。延髓腹外侧的神经元是多条反射通路的组成部分。A5细胞群内神经元的激活可产生复杂的交感和心血管反应模式。交感神经元的呼吸调节类型可能与其功能相关。中枢神经系统内的阿片类机制在对出血的心血管反应中很重要。血管紧张素II和心房利钠肽的中枢作用可能会减弱自发性高血压大鼠的压力感受器反射。