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[血液稀释监测]

[Monitoring in hemodilution].

作者信息

Singbartl G, Schleinzer W

机构信息

Abteilung Anästhesiologie, Intensiv- und Transfusionsmedizin, Endo-Klinik, Hamburg, BRD.

出版信息

Infusionsther Transfusionsmed. 1993 Aug;20(4):166-71.

PMID:8400797
Abstract

Normovolaemic haemodilution is an established part within the 'Concept of Autologous Transfusion'. According to the mechanisms to compensate for the dilution-induced anaemia, monitoring of haemodilution has to consider (1) maintenance of normovolaemia; (2) stability of the cardio-vascular system and of a normal pulmonary function; (3) an adequate myocardial oxygen supply. (1) Normovolaemia: Under routine clinical conditions normovolaemia is controlled by close monitoring of fluid balance (considering surgical blood loss, diuresis, and insensible perspiration). If the expected blood loss is > 2.0 litres, additional monitoring of the central venous pressure appears to be reasonable. It is not a single value of the central venous pressure (CVP) but rather its time-course that allows conclusions on changes of intravascular volume. (2) Cardio-vascular and pulmonary function: Pulmonary function is easily controlled by intermittent arterial blood gas analysis. Non-invasive and discontinuous or invasive and continuous blood pressure recording, respectively, are routinely used for monitoring of cardiovascular function. Heart rate together with the time-course of the CVP give additional information on the cardio-vascular system. Central-venous oxygen saturation is only a minor substitute for mixed venous oxygen saturation; however, its changes with time make it possible to draw conclusions on global haemodynamics and total body oxygen supply. However, in situations of extreme haemodilution--as in Jehova's witnesses--a pulmonary artery catheter has to be used for monitoring the cardio-vascular system as well as bulk oxygen parameters. (3) Myocardial oxygen supply: Monitoring for myocardial ischaemia is routinely performed by ECG. It is both the number and the kinds of leads chosen that give adequate information.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

正常血容量性血液稀释是“自体输血概念”中已确立的一部分。根据补偿稀释性贫血的机制,血液稀释的监测必须考虑:(1)维持正常血容量;(2)心血管系统和正常肺功能的稳定性;(3)充足的心肌氧供应。(1)正常血容量:在常规临床情况下,通过密切监测液体平衡(考虑手术失血、利尿和不显性出汗)来控制正常血容量。如果预期失血量>2.0升,额外监测中心静脉压似乎是合理的。不是中心静脉压(CVP)的单一值,而是其时间进程能让人得出血管内容量变化的结论。(2)心血管和肺功能:通过间歇性动脉血气分析可轻松控制肺功能。分别采用无创和间断或有创和连续血压记录来常规监测心血管功能。心率与CVP的时间进程可提供有关心血管系统的更多信息。中心静脉血氧饱和度只是混合静脉血氧饱和度的次要替代指标;然而,其随时间的变化使得能够得出关于整体血流动力学和全身氧供应的结论。然而,在极端血液稀释的情况下——如耶和华见证人的情况——必须使用肺动脉导管来监测心血管系统以及大量氧参数。(3)心肌氧供应:通过心电图常规监测心肌缺血。所选导联的数量和种类都能提供充分信息。(摘要截断于250字)

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