Loipführer A M, Reichlmayr-Lais A M, Kirchgessner M
Institut für Ernährungsphysiologie, Technische Universität München-Weihenstephan, Freising, Fed. Rep. of Germany.
J Trace Elem Electrolytes Health Dis. 1993 Mar;7(1):37-40.
The concentration of Ca(2+)-ions in erythrocytes of lead-depleted rats was estimated using the fluorescent Ca(2+)-indicator fura-2. The lead-depleted animals of the F1 generation showed an elevated Ca(2+)-concentration, whereas in the Po generation there was no difference in the Ca(2+)-concentration between depletion and control group. The elevation of Ca(2+)-ion concentration of lead-depleted rats could be caused by a reduction in Ca-Mg-ATPase activity in lead-depletion and could possibly lead to a decreased mean corpuscular volume (MCV) of erythrocytes.
使用荧光钙指示剂fura-2估计了低铅大鼠红细胞中钙离子（Ca(2+)）的浓度。F1代的低铅动物显示钙离子浓度升高，而在P0代中，低铅组和对照组之间的钙离子浓度没有差异。低铅大鼠钙离子浓度的升高可能是由于低铅状态下钙镁ATP酶活性降低所致，并且可能导致红细胞平均体积（MCV）减小。
