Krasnowska M, Smolik K, Małolepszy J
Katedry i Kliniki Chorób Wewnetrznych i Alergologii AM, Wrocławiu.
Pneumonol Alergol Pol. 1993;61(7-8):389-93.
The aim of this study was to demonstrate the differences in salbutamol's bronchodilating effect related to administration routes of the drug. Three different administration routes were assessed: salbutamol given by a MDI device, a nebulizer and intravenously. The following increases of FEV1 were seen after administration routes: MDI--12%, nebuliser--27%, intravenously--22%. These differences were statistically significant.
本研究的目的是证明沙丁胺醇的支气管扩张作用因药物给药途径不同而存在差异。评估了三种不同的给药途径：通过定量吸入器（MDI）装置给药、通过雾化器给药和静脉给药。给药后观察到第一秒用力呼气容积（FEV1）的增加情况如下：MDI给药后增加12%，雾化器给药后增加27%，静脉给药后增加22%。这些差异具有统计学意义。
