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[生理条件下小肠中不同葡萄糖吸收机制的相对作用]

[The relative role of different mechanisms of glucose absorption in the small intestine under physiological conditions].

作者信息

Gromova L V, Gruzdkov A A

出版信息

Fiziol Zh Im I M Sechenova. 1993 Jun;79(6):65-72.

PMID:8401656
Abstract

Chronic experiments in animals have shown that, even at the maximal glucose (75 mM) and maltose (37.5 mM) concentrations in the initial perfusate, the rate of glucose transfer by a solvent drug does not exceed 10 and 13 per cent, resp. of the total rate of glucose absorption in an isolated intestinal loop. The absorption of glucose under physiological conditions seems to be due mainly to its active transport across the apical membrane of the enterocytes.

摘要

动物慢性实验表明,即使在初始灌注液中葡萄糖(75 mM)和麦芽糖(37.5 mM)的浓度达到最大值时,溶剂药物介导的葡萄糖转运速率分别也不超过分离肠袢中葡萄糖总吸收速率的10%和13%。生理条件下葡萄糖的吸收似乎主要归因于其通过肠上皮细胞顶端膜的主动转运。

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