[The activity and properties of K-pNPphosphatase in membrane preparations of erythrocytes with different polypeptide compositions in Wistar, Wistar-Kyoto and SHR strain rats].

A higher K-pNPPase activity was found in erythrocyte membrane preparations from the SHR as compared with the Wistar rats. Removal of peripheral proteins from the membrane skeleton depressed the K-phosphatase activity and eliminated the difference between the SHR and Wistar rats. No activating effect of the ATP and Ca on the enzyme was found. The data obtained suggest that the proteins of the erythrocyte membrane skeleton are connected with regulation of the enzyme transport in the erythrocyte membranes of the SHR via a modulating effect of intracellular ATP and Ca.