Iacoangeli M, Roselli R, Prezioso A, Scerrati M, Rossi G F
Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy.
Br J Surg. 1993 Sep;80(9):1130-3. doi: 10.1002/bjs.1800800920.
A 'TGS' classification for supratentorial brain glioma is proposed, based on three parameters: tumour extension (T), histopathological grade (G) and extent of surgical resection (S). Two groups of patients were analysed: the first (n = 137) had tumour submitted to stereotactic biopsy; the second (n = 60) had malignant glioma operated on by craniotomy and tumor resection. All three staging parameters significantly influenced survival. Histopathological grade was the most significant factor, and the only independent variable on multivariate analysis, followed by extent of tumour and then extent of surgical resection. The data support the applicability of the proposed parameters for a staging classification of hemispheric brain glioma.
基于肿瘤扩展（T）、组织病理学分级（G）和手术切除范围（S）这三个参数，提出了一种幕上脑胶质瘤的“TGS”分类方法。分析了两组患者：第一组（n = 137）的肿瘤接受了立体定向活检；第二组（n = 60）的恶性胶质瘤接受了开颅手术和肿瘤切除术。所有三个分期参数均对生存率有显著影响。组织病理学分级是最显著的因素，也是多变量分析中唯一的独立变量，其次是肿瘤范围，然后是手术切除范围。这些数据支持所提出的参数适用于半球脑胶质瘤的分期分类。
