Tobias J D, Lowe S, O'Dell N, Holcomb G W
Department of Anesthesiology, Vanderbilt University, Nashville, Tennessee.
Can J Anaesth. 1993 Sep;40(9):879-82. doi: 10.1007/BF03009262.
When compared with conventional analgesic techniques, epidural anaesthesia not only provides improved analgesia, but also has several beneficial effects on the postoperative respiratory, cardiovascular, and metabolic status of the patient. Although the efficacy and safety of caudal and lumbar epidural anaesthesia in children has been demonstrated, there is little information concerning the use of thoracic epidural anaesthesia. The purpose of our review was to evaluate the safety of thoracic epidural anaesthesia in infants and children. We retrospectively reviewed our three-year experience with thoracic epidural anaesthesia for postoperative analgesia in children. Epidural catheters were placed at the thoracic level without difficulty in 63 children ranging in age from three months to 18 yr and in weight from 3.2 to 78 kg. Postoperative analgesia was provided by the continuous infusion of a bupivacaine/fentanyl mixture, supplemented with intermittent epidural fentanyl by bolus as needed. Epidural catheters were successfully placed in all patients. No inadvertent dural punctures were noted. No episodes of respiratory depression related to epidural analgesia occurred. Minor adverse effects including pruritus occurred in six patients, three of whom required pharmacological intervention with diphenhydramine. Our review suggests that this is a safe and effective method of postoperative analgesia following thoracic surgery in children.
与传统镇痛技术相比,硬膜外麻醉不仅能提供更好的镇痛效果,还对患者术后的呼吸、心血管和代谢状况有诸多有益影响。尽管骶管和腰段硬膜外麻醉在儿童中的有效性和安全性已得到证实,但关于胸段硬膜外麻醉应用的信息却很少。我们此次综述的目的是评估婴幼儿和儿童胸段硬膜外麻醉的安全性。我们回顾性分析了三年来对儿童进行胸段硬膜外麻醉用于术后镇痛的经验。在年龄从3个月至18岁、体重从3.2千克至78千克的63名儿童中,硬膜外导管均顺利置于胸段水平。术后镇痛通过持续输注布比卡因/芬太尼混合液,并根据需要间歇性推注硬膜外芬太尼来实现。所有患者的硬膜外导管均成功置入。未发现意外穿破硬脊膜的情况。未发生与硬膜外镇痛相关的呼吸抑制事件。6名患者出现了包括瘙痒在内的轻微不良反应,其中3名患者需要用苯海拉明进行药物干预。我们的综述表明,这是一种用于儿童胸段手术后镇痛的安全有效的方法。