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[脊椎动物视网膜水平细胞与光感受器之间反馈机制的模型]

[Model for the feedback mechanism between horizontal cells and photoreceptors of vertebrate retinas].

作者信息

Byzov A L

出版信息

Neirofiziologiia. 1977;9(1):86-94.

PMID:840332
Abstract

A model is proposed which is based on the hypothesis that the feedback between horizontal cells and photoreceptors is fulfilled by electric current generated by the subsynaptic membrane of horizontal cells and flowing partially through receptors. An important element of the model is nonlinearity of the presynaptic membrane of photoreceptors. The model reproduces such experimental data as depolarization of cones evoked by hyperpolarization of horizontal cells with a light annulus or extrinsic current, as well as some properties of current-voltage relations in cones and rods.

摘要

提出了一个模型,该模型基于这样的假设:水平细胞与光感受器之间的反馈是由水平细胞突触下膜产生并部分流经感受器的电流来实现的。该模型的一个重要元素是光感受器突触前膜的非线性。该模型再现了诸如用亮环或外源电流使水平细胞超极化从而诱发视锥细胞去极化等实验数据,以及视锥细胞和视杆细胞中电流 - 电压关系的一些特性。

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