Nair L A, Reynolds J C, Parkman H P, Ouyang A, Strom B L, Rosato E F, Cohen S
Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
Dig Dis Sci. 1993 Oct;38(10):1893-904. doi: 10.1007/BF01296115.
A retrospective cohort study was performed to assess risk factors, early clinical characteristics, and outcome of complications in patients undergoing pneumatic dilation. Of 178 patients with achalasia or diffuse esophageal spasm who underwent 236 dilations with a Browne-McHardy dilator, 16 patients experienced a complication (9.0%). Nine major complications developed: perforations (4), hematemesis (2), fever (2), and angina (1). A prior pneumatic dilation and use of inflation pressure > or = 11 PSI were independent risk factors by multivariate analysis for developing a complication. An esophagram immediately following the dilation identified three of the four perforations. Three postdilation findings were identified as indicators of patients with an increased risk of having developed a perforation: blood on the dilator, tachycardia, and prolonged chest pain lasting > 4 hr after dilation. In all patients incurring a major complication, one of the three indicators, or the complication itself was recognized within 5 hr of dilation. All patients with complications, including the four with perforation who received prompt surgical repair and esophagomyotomy, recovered uneventfully. The symptomatic relief of dysphagia in patients with perforation undergoing emergent surgical repair and esophagomyotomy was similar to patients undergoing elective esophagomyotomy.
(1) Pneumatic dilation is a safe treatment of achalasia, with a 1.7% risk of perforation. (2) The risk of developing a complication is increased by having had a previous pneumatic dilation or by use of inflation pressures > or = 11 psi. (3) All patients with a major complication were identified within 5 hr after dilation. (4) Complications following pneumatic dilation, if recognized and treated promptly, were not associated with adverse, long-term sequelae.
进行了一项回顾性队列研究,以评估接受气囊扩张术患者的危险因素、早期临床特征及并发症结局。在178例患有贲门失弛缓症或弥漫性食管痉挛并使用布朗 - 麦克哈迪扩张器进行了236次扩张的患者中,16例出现并发症(9.0%)。发生了9例严重并发症:穿孔(4例)、呕血(2例)、发热(2例)和心绞痛(1例)。多因素分析显示,既往气囊扩张术及使用充气压力≥11磅力/平方英寸是发生并发症的独立危险因素。扩张术后立即进行的食管造影发现了4例穿孔中的3例。确定了三项扩张术后表现为穿孔风险增加患者的指标:扩张器上有血迹、心动过速以及扩张后持续超过4小时的长时间胸痛。在所有发生严重并发症的患者中,三项指标之一或并发症本身在扩张后5小时内被识别。所有出现并发症的患者,包括4例接受了及时手术修复和食管肌层切开术的穿孔患者,均顺利康复。接受紧急手术修复和食管肌层切开术的穿孔患者吞咽困难症状缓解情况与接受择期食管肌层切开术的患者相似。
(1)气囊扩张术是治疗贲门失弛缓症的安全方法,穿孔风险为1.7%。(2)既往有气囊扩张术或使用充气压力≥11磅力/平方英寸会增加发生并发症的风险。(3)所有严重并发症患者在扩张后5小时内被识别。(4)气囊扩张术后的并发症若能及时识别并治疗,不会导致不良的长期后遗症。