Jyothi K, Susheela S, Kodali V R, Balakrishnan S, Seshaiah V
Department of Child Psychology, J.B.A.S. College for Women, University of Madras, Teynampet, India.
Diabetes Res Clin Pract. 1993 Jun;20(3):209-13. doi: 10.1016/0168-8227(93)90080-o.
Cognitive function was assessed in 22 diabetic and 39 healthy children, all in the age group of 6-12 years. Wechsler's coding, digit span test and Raven's colored progressive matrices were included in the battery of tests. The diabetic children underscored on all these tasks compared to the healthy children. The raw scores (mean +/- S.D.), of the diabetic and healthy children were: Wechsler's coding: 17.4 +/- 6.48, 37.4 +/- 9.33; digit span: 22.0 +/- 8.8, 44.1 +/- 7.67 and on Raven's A+AB+B: 16.2 +/- 3.5. 24.1 +/- 6.26; P < 0.001 in each instance, respectively. Duration of diabetes did not correlate with any of the test scores. No significant differences were noted between the early onset (IDDM starting before the age of 5 years) and late onset (IDDM starting after 5 years) diabetic children in their performance. We attribute the very low scores in our diabetic children to the psycho-social factors in addition to the metabolic control.
(1) specific cognitive dysfunction is present in children with IDDM compared to the healthy children; (2) duration of diabetes did not correlate with cognitive function scores; (3) IDDM manifesting after the age of 5 years also had hitherto unknown detrimental effects on the cognitive process.
对22名糖尿病儿童和39名健康儿童进行了认知功能评估，所有儿童年龄均在6至12岁之间。测试组合包括韦氏编码、数字广度测试和瑞文彩色渐进矩阵测试。与健康儿童相比，糖尿病儿童在所有这些任务上的表现都较差。糖尿病儿童和健康儿童的原始分数（平均值±标准差）分别为：韦氏编码：17.4±6.48，37.4±9.33；数字广度：22.0±8.8，44.1±7.67；瑞文A+AB+B：16.2±3.5，24.1±6.26；每种情况的P均<0.001。糖尿病病程与任何测试分数均无相关性。早发（5岁前发病的胰岛素依赖型糖尿病）和晚发（5岁后发病的胰岛素依赖型糖尿病）糖尿病儿童在表现上没有显著差异。除代谢控制外，我们将糖尿病儿童的极低分数归因于心理社会因素。
（1）与健康儿童相比，胰岛素依赖型糖尿病儿童存在特定的认知功能障碍；（2）糖尿病病程与认知功能分数无关；（3）5岁后发病的胰岛素依赖型糖尿病对认知过程也有迄今未知的有害影响。
