6至12岁正常儿童血清降钙素与血液矿物质的相互关系。

Serum calcitonin and blood mineral interrelationships in normal children aged six to twelve years.

作者信息

Shainkin-Kerstenbaum R, Funkenstein B, Conforti A, Shani S, Berlyne G M

出版信息

Pediatr Res. 1977 Feb;11(2):112-6. doi: 10.1203/00006450-197702000-00006.

DOI:10.1203/00006450-197702000-00006

Abstract

Simultaneous measurements of serum immunoreactive thyrocalcitonin (iTCT), immunoreactive parathyroid hormone (iPTH), calcium, inorganic phosphate, magnesium, and alkaline phosphatase were made in 37 normal children whose ages ranged from 6-12 years. Between the ages of 6 and 12 there is a statistically significant rise in serum iTCT levels (r = 0.4638; P less than 0.01), and a fall in serum iPTH levels (r = 0.4976; P less than 0.01). There is a highly significant inverse correlation between serum iTCT and iPTH levels (r = 0.5248; P less than 0.005). Serum iTCT levels were inversely correlated with phosphate levels (r = 0.4989; P less than 0.01), the latter being age dependent and falling significantly between the ages of 6 and 12 (r = 0.4802; P less than 0.001). There was no significant relationship between serum calcium levels and iTCT, iPTH, or age. Serum magnesium levels were not correlated with calcium, iTCT, or iPTH levels.

摘要

对37名年龄在6至12岁的正常儿童同时进行了血清免疫反应性甲状腺降钙素（iTCT）、免疫反应性甲状旁腺激素（iPTH）、钙、无机磷、镁和碱性磷酸酶的测量。在6至12岁之间，血清iTCT水平有统计学上的显著升高（r = 0.4638；P小于0.01），血清iPTH水平下降（r = 0.4976；P小于0.01）。血清iTCT和iPTH水平之间存在高度显著的负相关（r = 0.5248；P小于0.005）。血清iTCT水平与磷酸盐水平呈负相关（r = 0.4989；P小于0.01）——磷酸盐水平与年龄相关，在6至12岁之间显著下降（r = 0.4802；P小于0.001）。血清钙水平与iTCT、iPTH或年龄之间没有显著关系。血清镁水平与钙、iTCT或iPTH水平无关。