Stroińska-Kusiowa B
J Neurol. 1979 Jan 30;220(1):65-70. doi: 10.1007/BF00313149.
The behavior of the capillaries of denervated, reinnervated and hypertrophic muscle of rats was investigated with aid of microangiography. The vessels of the denervated muscle ran irregular, formed spirals and their parallel position to the muscle fibers was completely lost. The appearance of vessels after 3 and 6 weeks in the reinnervated muscle was similar to that observed after denervation. The pattern of vessels became more normal 3 months after the operation. The hypertrophic exercised muscles had an irregular course but with less tendency to spiral formation than atropic muscles. Their caliber was enlarged. The results showed that in denervated, reinnervated and hypertrophic muscle similar changes in capillary vessels develop. The vessels lose their parallel position to the muscle fibers and have a tendency to spiralization. The changes probably contributed to impairment of the circulation.
借助微血管造影术,对大鼠去神经支配、重新神经支配和肥大肌肉的毛细血管行为进行了研究。去神经支配肌肉的血管走行不规则,形成螺旋状,且与肌纤维的平行位置完全丧失。重新神经支配肌肉在3周和6周后的血管外观与去神经支配后观察到的相似。术后3个月血管形态变得更正常。肥大的运动肌肉走行不规则,但比萎缩肌肉形成螺旋的倾向小。其管径增大。结果表明,在去神经支配、重新神经支配和肥大的肌肉中,毛细血管会发生类似的变化。血管失去了与肌纤维的平行位置,并趋于螺旋化。这些变化可能导致了循环障碍。