Nagel M, Holtkamp B, Hagmuller E, Saeger H D
Clinique Chirurgicale Universitaire, de Mannheim, Allemagne.
J Chir (Paris). 1993 Jun-Jul;130(6-7):300-3.
Between 1982 and 1990, 1027 women and 13 men were operated upon for cancer of the breast. Analysis failed to show any difference with sex for age, localization or symptomatology. Distribution by stage, as defined by the U.I.C.C., showed a higher incidence of stage III in the men and of stage II in the women. Treatment consisted of a modified Patey type radical mastectomy in the men, a more limited intervention being applied in 20% of the women. After a mean follow up of 62 months, none of the men had died of their breast cancer. The recurrence rate was 16%. Results in this series and in those reported in the literature emphasize the decisive prognostic value of primary surgical treatment. Complementary hormone therapy with tamoxifen is particularly indicated, since 90% of the patients had positive estrogen hormone receptors.
1982年至1990年间，1027名女性和13名男性接受了乳腺癌手术。分析结果显示，在年龄、肿瘤位置或症状方面，性别之间没有差异。按照国际抗癌联盟（U.I.C.C.）定义的分期分布显示，男性中III期的发病率较高，女性中II期的发病率较高。男性的治疗方式为改良的佩蒂（Patey）式根治性乳房切除术，20%的女性采用了更为有限的干预措施。平均随访62个月后，没有男性死于乳腺癌。复发率为16%。本系列研究结果以及文献报道的结果强调了初次手术治疗的决定性预后价值。鉴于90%的患者雌激素受体呈阳性，特别推荐使用他莫昔芬进行辅助激素治疗。
