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[日本患者大隐静脉移植血管的长期通畅率及静脉移植血管病变]

[The long-term patency rate of saphenous vein grafts and vein graft disease in Japanese patients].

作者信息

Horii T, Suma H, Wanibuchi Y, Fukuda S, Kigawa I

机构信息

Department of Cardiovascular Surgery, Mitsui Memorial Hospital, Tokyo, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1993 Sep;41(9):1447-51.

PMID:8409597
Abstract

While annual attrition and high break-down rate of saphenous vein graft (SVG) used for CABG has widely noted in Western countries, no sizable studies have yet available in Japan. We studied 142 SVGs of 77 pts, which we divided into two groups; 80 SVGs of 44 pts in mid-term period (5 to 8 years after surgery) and 62 SVGs of 33 pts in long-term period (9 to 17 years after surgery). The patency rate of SVGs was 69% in mid-term and 77% in long-term. Whereas these patency rates at each periods were superior to those reported from USA and European countries, a quarter of SVGs in mid-term period and a half in long-term period had significant stenotic changes (over 50%). Of patent SVGs, diseased SVGs reached 36% in mid-term period and 73% in long-term period. In conclusion, although the patency rate of SVGs in Japanese patients was higher than that of the Western countries, vein graft disease apparently occurred in a large proportion of patent SVGs.

摘要

虽然西方国家广泛注意到用于冠状动脉旁路移植术(CABG)的大隐静脉移植物(SVG)的年度损耗和高故障率,但日本尚未有大规模研究。我们研究了77例患者的142条SVG,将其分为两组;44例患者的80条SVG处于中期(术后5至8年),33例患者的62条SVG处于长期(术后9至17年)。SVG的通畅率中期为69%,长期为77%。虽然各时期的这些通畅率优于美国和欧洲国家报告的通畅率,但中期四分之一的SVG和长期二分之一的SVG有明显的狭窄变化(超过50%)。在通畅的SVG中,病变的SVG在中期达到36%,在长期达到73%。总之,虽然日本患者中SVG的通畅率高于西方国家,但在很大比例的通畅SVG中明显发生了静脉移植物病变。

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