Whiteman D, Gropper P T, Wirtz P, Monk P
Vancouver General Hospital, British Columbia, Canada.
J Hand Surg Br. 1993 Aug;18(4):487-90. doi: 10.1016/0266-7681(93)90154-8.
The results of 20 consecutive cases of bone defects of the hand treated by curettage and implantation of demineralized bone powder compare well with a similarly matched retrospective group managed with autogenous grafts and curettage alone. Results revealed "excellent" (16 patients) or "good" bone healing (4 patients) in the bone powder group on independent radiographic evaluation. Bone bridging was noted at an average of 9.9 weeks. All defects healed without recurrence, resorption or refracture, with follow-up of 4 to 36 months. In the conventionally managed retrospective group there was a 25% failure rate necessitating re-operation. Demineralized bone powder provides a rapid, safe and effective method of management of bone defects of the hand.
对20例手部骨缺损患者采用刮除术并植入脱矿骨粉进行治疗，其结果与另一组采用自体骨移植和单纯刮除术治疗的、年龄与病情相匹配的回顾性研究组相比，效果良好。独立影像学评估结果显示，骨粉组有16例患者实现“优秀”、4例患者实现“良好”的骨愈合。平均在9.9周时可见骨桥形成。随访4至36个月，所有缺损均愈合，无复发、吸收或再骨折情况。在传统治疗的回顾性研究组中，有25%的失败率，需要再次手术。脱矿骨粉为手部骨缺损的治疗提供了一种快速、安全且有效的方法。
