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用于广泛耳廓恶性肿瘤的颞骨外侧切除术。四十年来有什么变化吗?

Lateral temporal bone resection for extensive pinnal malignancy. Has anything changed in forty years?

作者信息

Shotton J C, Sergeant R J, Tanner N S, Allen J P

机构信息

Department of Otolaryngology, Kent and Sussex Hospital, Tunbridge Wells.

出版信息

J Laryngol Otol. 1993 Aug;107(8):697-702. doi: 10.1017/s002221510012417x.

Abstract

This paper offers an account of the contemporary surgical approach to advanced tumours of the external ear based on a series of 11 patients. There were eight squamous, two basal cell carcinomas and one mucoepidermoid tumour. The traditional method of excision was slightly modified by performing microsurgical dissection of the lateral part of the temporal bone rather than chisel osteotomies, and then including it en bloc with the involved soft tissues. The defect was then closed using a scalp or myocutaneous flap and this combination of otological and reconstructive expertise has proved satisfactory. Four patients are alive with no evidence of disease a mean of 4.2 (range 1.0-7.0) years from surgery: two patients who remained free of disease have subsequently died of unrelated conditions 12 and 24 months post-operatively, and in three cases death from recurrent disease occurred a mean of 1.4 (range 0.9-2.1) years after our surgery. There were two post-operative deaths. Based on the actuarial survival of 36 per cent and a successful disease clearance rate of 54 per cent, our conclusion is that the outlook of this condition has not dramatically improved since the original descriptions of the management of this problem first appeared, although intervention remains justifiable because of the potential curability and relief of symptoms.

摘要

本文基于11例患者的系列病例,介绍了当代对外耳晚期肿瘤的手术治疗方法。其中有8例鳞状细胞癌、2例基底细胞癌和1例黏液表皮样瘤。传统的切除方法略有改进,即对颞骨外侧部分进行显微外科解剖,而非凿骨截骨术,然后将其与受累软组织整块切除。然后使用头皮瓣或肌皮瓣封闭缺损,这种耳科和重建技术的结合已被证明是令人满意的。4例患者存活,术后平均4.2年(范围1.0 - 7.0年)无疾病证据:2例无疾病复发的患者随后分别在术后12个月和24个月死于无关疾病,3例患者术后平均1.4年(范围0.9 - 2.1年)死于疾病复发。有2例术后死亡。基于36%的精算生存率和54%的成功疾病清除率,我们的结论是,自从首次出现对该问题治疗的最初描述以来,这种疾病的预后并没有显著改善,尽管由于潜在的可治愈性和症状缓解,干预仍然是合理的。

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