Poe N D, Cohen M B, Yanda R L
Radiology. 1977 Mar;122(3):739-46. doi: 10.1148/122.3.739.
Lung scintigraphy following radioaerosol inhalation reveals evidence of airway disease and regions of decreased ventilation. In obstructive pulmonary diseases, aerosol deposition can be so excessive that lung parenchyma is not visualized immediately after radioaerosol administration. Most of the tracer which is deposited is cleared within hours, but the aerosol reaching the alveoli is retained with a half-life in excess of 2 weeks. If imaging is repeated 8-24 hours after inhalation, abnormal bronchi will usually be cleared of tracer, and regional ventilation defects can be visualized.
放射性气溶胶吸入后的肺闪烁扫描可显示气道疾病及通气减少区域的证据。在阻塞性肺部疾病中，气溶胶沉积可能过多，以至于在给予放射性气溶胶后立即无法显示肺实质。沉积的大部分示踪剂会在数小时内清除，但到达肺泡的气溶胶会以超过2周的半衰期留存。如果在吸入后8 - 24小时重复成像，异常支气管通常会清除示踪剂，并且可以看到局部通气缺陷。
