Dawson N V, Connors A F, Speroff T, Kemka A, Shaw P, Arkes H R
Department of Medicine, Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH 44109-1998.
Med Decis Making. 1993 Jul-Sep;13(3):258-66. doi: 10.1177/0272989X9301300314.
Prior to right-heart catheterization of 846 patients, 198 study physicians estimated values of pulmonary capillary wedge pressure (WP), cardiac index (Cl), and systemic vascular resistance index (VRI). The physicians also expressed their confidence in these estimates. Actual values of WP, Cl, and VRI as determined by catheterization enabled the authors to evaluate the quality of the physicians' judgments. The discrimination of the judgments was modest; areas under the ROC curves for WP, Cl, and VRI were 0.724, 0.681, and 0.656, respectively. Calculated using clinically relevant cutoff values, sensitivities were 64%, 50%, and 64%, and specificities were 71%, 75%, and 63%, respectively. Calibration of the estimates of WP, Cl, and VRI was also modest; physicians tended to overestimate low values and underestimate high values. Physicians were generally confident of their estimates, but there was no relation between confidence and accuracy. Experienced physicians were no more accurate than less experienced ones, although they were significantly more confident. The authors conclude that physicians should not use their levels of confidence in their subjective estimates of cardiac function in deciding whether to base therapy on these estimates.
在对846例患者进行右心导管插入术之前,198名参与研究的医生对肺毛细血管楔压(WP)、心脏指数(Cl)和体循环血管阻力指数(VRI)进行了估计。医生们还表达了他们对这些估计值的信心。通过导管插入术确定的WP、Cl和VRI的实际值使作者能够评估医生判断的质量。判断的辨别力一般;WP、Cl和VRI的ROC曲线下面积分别为0.724、0.681和0.656。使用临床相关的临界值计算,敏感性分别为64%、50%和64%,特异性分别为71%、75%和63%。WP、Cl和VRI估计值的校准也一般;医生们倾向于高估低值而低估高值。医生们总体上对自己的估计有信心,但信心与准确性之间没有关系。经验丰富的医生并不比经验不足的医生更准确,尽管他们的信心明显更强。作者得出结论,医生在决定是否基于这些估计进行治疗时,不应将自己对心功能主观估计的信心程度作为依据。