O'Brien C P, Testa T, O'Brien T J, Brady J P, Wells B
Science. 1977 Mar 11;195(4282):1000-2. doi: 10.1126/science.841320.
Subjective and physiological manifestations of the narcotic withdrawal syndrome were produced as a conditioned response. Withdrawal reactions precipitated by the narcotic antagonist naloxone in methadone-dependent volunteers were the unconditioned response. These data support clinical anecdotes of withdrawal symptoms occurring in former addicts when they return to their drug-related environment.
麻醉品戒断综合征的主观和生理表现被作为一种条件反应产生。在美沙酮依赖的志愿者中，由麻醉拮抗剂纳洛酮引发的戒断反应是无条件反应。这些数据支持了以前的成瘾者回到与毒品相关的环境中时出现戒断症状的临床轶事。
