Oge A E, Yazici J, Boyaciyan A, Tanyeri S, Celik M, Konyalioğlu R, Baslo A
Department of Neurology, University of Istanbul, Istanbul Faculty of Medicine, Turkey.
Muscle Nerve. 1993 Nov;16(11):1154-60. doi: 10.1002/mus.880161103.
The facial nerve was stimulated trascranially with a magnetic stimulator in 14 normal controls, 14 hemifacial spasm patients, and 16 post-facial-palsy synkinesis patients. Magnetic stimulation in normal controls revealed muscle responses which had latencies with a mean value of 4.99 +/- 0.49 ms and amplitudes of 2.41 +/- 1.08 mV. In the same group, transosseal conduction time was calculated to be 1.20 +/- 0.13 ms. In the hemifacial spasm group, the amplitudes of the responses on the affected sides were lower as compared to the unaffected sides (mean values 1.78 vs. 2.41 mV, P = 0.01). Also, the threshold to magnetic stimulation was elevated on the affected sides. These findings are suggestive of the presence of a hypoexcitability to magnetic stimulation in the root entry zone. In the post-facial-palsy synkinesis patients, magnetic stimulation of the affected sides resulted in responses with long latencies and low amplitudes (mean latency 6.34 ms, mean amplitude 0.90 mV). In the recordings made with magnetic stimulation, the difference of the latencies between the two sides was larger as compared to those obtained by electrical stimulation. The transosseal conduction time was also remarkably prolonged on the affected side. These findings may suggest that magnetic stimulation can be an effective method of showing intracranially located lesions of the facial nerve.
在14名正常对照者、14名半面痉挛患者和16名面瘫后联动患者中,使用磁刺激器经颅刺激面神经。正常对照者的磁刺激显示肌肉反应,其潜伏期平均值为4.99±0.49毫秒,波幅为2.41±1.08毫伏。在同一组中,经骨传导时间计算为1.20±0.13毫秒。在半面痉挛组中,患侧反应的波幅低于未患侧(平均值分别为1.78和2.41毫伏,P = 0.01)。此外,患侧磁刺激阈值升高。这些发现提示在神经根入区存在对磁刺激的兴奋性降低。在面瘫后联动患者中,患侧的磁刺激导致反应潜伏期长且波幅低(平均潜伏期6.34毫秒,平均波幅0.90毫伏)。在磁刺激记录中,两侧潜伏期的差异比电刺激时更大。患侧的经骨传导时间也显著延长。这些发现可能表明磁刺激可以是显示面神经颅内病变的有效方法。