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[意大利北部移植项目(NITp)中参与器官获取用于移植活动的医院的组织问题。复苏麻醉医师协作组]

[The organizational problems of the hospitals of the Nord Italia Transplant Program (NITp) engaged in the activities of organ retrieval for transplantation. The Collaborative Group of Resuscitation Anesthetists].

作者信息

Iapichino G, Piccolo G, Bonelli S, Pizzi C, Gianelli Castiglione A, Gravame V, Guarino A, Licata C, Sarpellon M, Servadio G

机构信息

Centro Trasfusionale e di Immunologia dei Trapianti, Ospedale Maggiore Policlinico di Milano.

出版信息

Minerva Anestesiol. 1993 Jun;59(6):327-34.

PMID:8414094
Abstract

If the quality of results of organ transplantation in NITp is highly satisfactory, the same cannot be said for the number of transplants performed, which only cover 20-25% of the requirement. To understand the causes of organ shortage, a study group of Anaesthesiologists and Transplant Coordinators from the North Italy Transplant Program (NITp) investigated, through a questionnaire addressed to the Heads of 103 Intensive Care Units (ICU) in 92 Hospitals in the NITp area, some of the organizational problems linked to donor identification and treatment and to organ retrieval. The questionnaire took into consideration the number of possible donors identified in 1990, those retrieved and the causes for non retrieving organs and examined a number of variables linked both to retrieval and to ICUs and Hospitals organization. The results show that potential donors were 461: 143 (31%) were used, 138 (30%) were lost due to family opposition to organ donation, 192 (20%) for clinical reasons and 88 (19%) for organizational reasons. The latter figure represents 5% of non retrieval in the most active ICUs and increases to 50% in the Hospitals that had procured no donors in 1990. The main obstacles for ICUs to procure organ donors are: convey the Medical-Legal Committee, carry out of complicated administrative procedures, availability of round the clock specialized equipment for neurological assessment (especially for ICU outside Neurosurgical and Neurological departments), inadequate number of medical and nursing staff, most of all at night, and finally the difficulty in the management of non-traumatic cerebrovascular patients.

摘要

如果说国家移植计划(NITp)中器官移植的结果质量非常令人满意,那么所进行的移植数量却并非如此,其仅满足了20%至25%的需求。为了解器官短缺的原因,来自意大利北部移植计划(NITp)的一个麻醉师和移植协调员研究小组,通过向NITp地区92家医院的103个重症监护病房(ICU)主任发放问卷,调查了一些与供体识别、治疗以及器官获取相关的组织问题。该问卷考虑了1990年识别出的潜在供体数量、获取的供体数量以及未获取器官的原因,并研究了一些与获取以及ICU和医院组织相关的变量。结果显示,潜在供体有461名:143名(31%)被利用,138名(30%)因家属反对器官捐赠而流失,192名(20%)因临床原因流失,88名(19%)因组织原因流失。后一数字在最活跃的ICU中占未获取情况的5%,而在1990年未获取任何供体的医院中则增至50%。ICU获取器官供体的主要障碍包括:向医学 - 法律委员会传达信息、执行复杂的行政程序、全天候配备用于神经评估的专业设备(尤其是神经外科和神经内科以外的ICU)、医护人员数量不足(尤其是在夜间),以及最后对非创伤性脑血管病患者的管理困难。

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