Ferreri S, Chiappa A, Cassolini G M, Fantoni A, Panazzolo A
Divisione di Ostetricia e Ginecologia, Ospedale, Degli Infermi di Rivoli TO.
Minerva Ginecol. 1993 Jul-Aug;45(7-8):343-8.
The paper examined the efficacy of transvaginal sonography in measuring the endometrium in menopausal women. The study included 50 women, both asymptomatic and with metrorrhagia, all of whom had been in menopause for at least 1 year and were under 75 years old. In symptomatic patients sonographic findings were compared with histological tests. Histological correlation was only performed in asymptomatic patients with endometrial findings of over 8 mm or in those undergoing surgery for other pathologies. Sonography revealed a good level of correlation with histological findings. Endometrial lines measuring less than 8 mm had no pathological significance. On the contrary, in those cases over 8 mm it was important to evaluate the overall morphological significance of sonographic findings and for this purpose histological diagnosis was necessary. Ten hyperplastic forms and 2 endometrial adenocarcinoma were diagnosed in this group. In terms of the sonographic image the hyperplastic forms appeared as a thick, highly reflective and well defined endometrial layer; on the contrary, carcinoma appeared as an irregular, highly reflective area with the loss of the hypoechogenic peripheral halo. The authors conclude that this easily performed and minimally invasive method is of value as as screening method for endometrial carcinoma and should be recommended for women receiving replacement therapy.
该论文研究了经阴道超声检查在测量绝经后女性子宫内膜方面的有效性。该研究纳入了50名女性，包括无症状和有子宫出血的女性，她们均已绝经至少1年且年龄在75岁以下。对有症状的患者，将超声检查结果与组织学检查进行了比较。仅对子宫内膜厚度超过8mm的无症状患者或因其他病理情况接受手术的患者进行了组织学相关性分析。超声检查显示与组织学结果具有良好的相关性。子宫内膜线小于8mm无病理意义。相反，在那些超过8mm的病例中，评估超声检查结果的整体形态学意义很重要，为此组织学诊断是必要的。该组诊断出10例增生性病变和2例子宫内膜腺癌。就超声图像而言，增生性病变表现为增厚、高回声且边界清晰的子宫内膜层；相反，癌表现为不规则、高回声区域，低回声外周晕消失。作者得出结论，这种操作简便且微创的方法作为子宫内膜癌的筛查方法具有价值，应推荐给接受替代疗法的女性。
