Osmers R G, Osmers M, Kuhn W
Department of Obstetrics and Gynecology, University of Göttingen, Germany.
Ultrasound Obstet Gynecol. 1995 Aug;6(2):103-7. doi: 10.1046/j.1469-0705.1995.06020103.x.
In the period between 1985 and 1991, 83 postmenopausal women with endometrial cancer were examined by transvaginal sonography. None of them were on hormone replacement therapy and all had amenorrhea of more than 2 years. Twenty-two were asymptomatic and had an endometrial cancer detected by transvaginal sonography and 61 showed atypical bleeding as their only clinical symptom. Women with asymptomatic endometrial cancers detected by transvaginal sonography exhibited significantly less mean myometrial tumor infiltration and more well-differentiated tumors than those with atypical bleeding (4 mm and 45% compared with 10 mm and 18%, respectively). In 75% of the cases the estimation by transvaginal sonography of tumor stage completely agreed with the histological staging. These preliminary data show that asymptomatic endometrial cancers screened by transvaginal sonography are likely to have a better prognosis than symptomatic cancers. Furthermore, transvaginal sonography can be used as a reliable tool for tumor staging prior to surgery or radiotherapy.
在1985年至1991年期间，对83名绝经后子宫内膜癌女性进行了经阴道超声检查。她们均未接受激素替代疗法，且闭经均超过2年。22名无症状女性经阴道超声检查发现患有子宫内膜癌，61名仅表现为非典型出血这一临床症状。经阴道超声检查发现的无症状子宫内膜癌女性，其平均肌层肿瘤浸润明显少于非典型出血女性，且高分化肿瘤更多（分别为4毫米和45%，而后者为10毫米和18%）。在75%的病例中，经阴道超声检查对肿瘤分期的估计与组织学分期完全一致。这些初步数据表明，经阴道超声筛查出的无症状子宫内膜癌预后可能比有症状的癌症更好。此外，经阴道超声可作为手术或放疗前肿瘤分期的可靠工具。
