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阿根廷儿童急性下呼吸道感染:一项为期40个月的临床和流行病学研究。

Acute lower respiratory infection in Argentinian children: a 40 month clinical and epidemiological study.

作者信息

Murtagh P, Cerqueiro C, Halac A, Avila M, Salomón H, Weissenbacher M

机构信息

Dr. Ricardo Gutierrez Hospital, Buenos Aires, Argentina.

出版信息

Pediatr Pulmonol. 1993 Jul;16(1):1-8. doi: 10.1002/ppul.1950160102.

Abstract

In a total of 1,003 children (805 inpatients and 198 outpatients) with acute lower respiratory infections (ALRI), clinical, social, and environmental data were analyzed. The major clinical entities were bronchiolitis, pneumonia, bronchitis, and laryngitis. The first two of these predominated in inpatients; pneumonia and bronchitis were more common in older children, while bronchiolitis was observed in infants. Respiratory rates of > 50/min. were more common in younger children and in cases with bronchiolitis and bronchitis. Retractions showed markedly less age-dependent variations and were present in all severe cases with different clinical diagnoses. Retractions alone or associated with cyanosis were the best indicators for severity of ALRI. Among outpatients, fever and wheezing were more common; inpatients were younger, more frequently malnourished, and from a lower socioeconomic level; family history of chronic bronchitis, crowding, and parental smoking also prevailed in this group. Family asthma and exposure to domestic aerosols was more common among outpatients. Prematurity rate (17 and 15%) of all ALRI cases was twice that of the general pediatric population and a significant difference existed between in- and outpatients under 6 months of age when perinatal respiratory pathologies predominated among inpatients. It is suggested to consider the need for assessing personal, family, and environmental risk factors in addition to clinical signs and symptoms when severe cases of ALRI are evaluated.

摘要

对总共1003名患有急性下呼吸道感染(ALRI)的儿童(805名住院患儿和198名门诊患儿)的临床、社会和环境数据进行了分析。主要的临床病症为细支气管炎、肺炎、支气管炎和喉炎。前两种病症在住院患儿中占主导;肺炎和支气管炎在年龄较大的儿童中更常见,而细支气管炎多见于婴儿。呼吸频率>50次/分钟在年龄较小的儿童以及患有细支气管炎和支气管炎的病例中更为常见。胸廓凹陷的年龄依赖性差异明显较小,且在所有不同临床诊断的重症病例中均有出现。单独的胸廓凹陷或伴有发绀是ALRI严重程度的最佳指标。在门诊患儿中,发热和喘息更为常见;住院患儿年龄更小,营养不良更为频繁,且社会经济水平较低;该组中慢性支气管炎家族史、拥挤和父母吸烟的情况也更为普遍。门诊患儿中家族性哮喘和接触家用气雾剂的情况更为常见。所有ALRI病例的早产率(17%和15%)是普通儿科人群的两倍,且在6个月以下的住院患儿和门诊患儿之间存在显著差异,住院患儿中围产期呼吸道疾病更为常见。建议在评估ALRI重症病例时,除了临床体征和症状外,还应考虑评估个人、家庭和环境风险因素。

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