Scoutt L M, McCauley T R, Flynn S D, Luthringer D J, McCarthy S M
Department of Diagnostic Imaging, Yale University School of Medicine, New Haven, CT 06510.
Radiology. 1993 Jan;186(1):159-62. doi: 10.1148/radiology.186.1.8416558.
High-resolution magnetic resonance (MR) images of nine hysterectomy specimens were correlated with light microscopy, computer-aided image analysis, and immunohistochemical examination to investigate the histologic counterparts of the zonal anatomy of the cervix. A central stripe of high signal intensity, a surrounding middle layer of low signal intensity, and an outer layer of intermediate signal intensity were found in all specimens. Histologic correlation indicated that the central stripe most likely represents the secretions in the canal, the cervical mucosa, and the plicae palmatae; the other two layers represent fibromuscular stroma. The percentage of nuclear area in the inner zone of the fibromuscular stroma is 2.5 times greater than in the outer zone, which may account for the lower signal intensity of the inner zone. No difference in distribution of collagen, laminin, and fibronectin (common components of the extracellular matrix) was found between the two zones of the cervical fibromuscular stroma.
对九个子宫切除标本的高分辨率磁共振（MR）图像与光学显微镜检查、计算机辅助图像分析及免疫组织化学检查进行对比，以研究子宫颈分层解剖结构的组织学对应情况。在所有标本中均发现一条高信号强度的中央带、一层围绕其的低信号强度中间层以及一层中等信号强度的外层。组织学对比表明，中央带很可能代表管腔内的分泌物、宫颈黏膜及掌状皱襞；另外两层代表纤维肌性基质。纤维肌性基质内层的核面积百分比比外层大2.5倍，这可能是内层信号强度较低的原因。在宫颈纤维肌性基质的两个区域之间，未发现胶原蛋白、层粘连蛋白和纤连蛋白（细胞外基质的常见成分）分布存在差异。
