Cox H D, Deshon G E, Mittemeyer B T, Condon B, Balance D
Urology. 1977 Feb;9(2):164-9. doi: 10.1016/0090-4295(77)90188-1.
The combination of fentanyl citrate (Sublimaze) and diazepam (Valium) was evaluated for efficacy of analgesia, sedation, and safety in 1,008 predominately outpatient urologic procedures. These procedures included prostate biopsies, basket extractions of ureteral calculi, internal urethrotomies, and cystourethroscopies. Ninety-two per cent were judged to be successful with regard to adequate tranquilization and relief of pain. No detrimental effects were seen with the recommmended method and dosage. This drug combination provides the clinician with an effective and safe alternative to local, general, or spinal anesthesia for many routine urologic procedures and allows them to becom true office procedures.
对枸橼酸芬太尼(舒芬太尼)和地西泮(安定)联合使用在1008例主要为门诊泌尿外科手术中的镇痛、镇静效果及安全性进行了评估。这些手术包括前列腺活检、输尿管结石篮式取石术、内尿道切开术和膀胱尿道镜检查。92%的患者在镇静和疼痛缓解方面被判定为成功。按照推荐的方法和剂量使用未观察到有害影响。这种药物组合为临床医生在许多常规泌尿外科手术中提供了一种有效且安全的替代局部、全身或脊髓麻醉的方法,并使这些手术能够真正在门诊进行。