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Japanese guidelines for mutagenicity testing. Ministry of Agriculture, Forestry and Fisheries; Ministry of Health and Welfare; Ministry of Labor.

作者信息

Sofuni T

机构信息

Division of Genetics and Mutagenesis, National Institute of Hygienic Sciences, Tokyo, Japan.

出版信息

Environ Mol Mutagen. 1993;21(1):2-7; discussion 46-57. doi: 10.1002/em.2850210103.

DOI:10.1002/em.2850210103
PMID:8419152
Abstract

Several Japanese agencies are required to perform mutagenicity tests according to regulatory guidelines. Although each agency's guidelines address a specific purpose, the experimental principles behind them are similar, and general methodological recommendations have been issued by the Ministry of Agriculture, Forestry, and Fisheries [1985]; Ministry of Health and Welfare [1990]; Ministry of Labor [1991]; and Ministry of Health and Welfare [1992]. Four major guidelines for mutagenicity testing in Japan and some amendments are briefly introduced. In addition, several procedures in Japanese guidelines that differ from those of other countries or organizations are discussed.

摘要

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