Cascino T L
Department of Neurology, Mayo Clinic, Rochester, Minnesota.
Med Clin North Am. 1993 Jan;77(1):265-78. doi: 10.1016/s0025-7125(16)30283-8.
Neurologic complications of systemic cancer are common. Metastatic complications include intracranial metastasis, spinal metastasis, leptomeningeal metastasis, and metastasis to peripheral nerves. Treatment is often effective in preventing further neurologic disability and pain. Early diagnosis is important. Nonmetastatic complications of systemic cancer include a wide variety of neurologic illnesses that can also occur in the noncancer population. The most common is toxic metabolic encephalopathy. Other nonmetastatic complications include cerebrovascular complications, complications of treatment, immunocompromised infections, and paraneoplastic syndromes.
全身性癌症的神经系统并发症很常见。转移性并发症包括颅内转移、脊髓转移、软脑膜转移和周围神经转移。治疗通常能有效预防进一步的神经功能障碍和疼痛。早期诊断很重要。全身性癌症的非转移性并发症包括多种也可发生于非癌症人群的神经系统疾病。最常见的是中毒性代谢性脑病。其他非转移性并发症包括脑血管并发症、治疗并发症、免疫功能低下感染和副肿瘤综合征。
