Fanni Salvatore Claudio, Greco Giuseppe, Rossi Sara, Aghakhanyan Gayane, Masala Salvatore, Scaglione Mariano, Tonerini Michele, Neri Emanuele
Department of Translational Research, Academic Radiology, University of Pisa, 56126 Pisa, Italy.
Department of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Explor Target Antitumor Ther. 2023;4(2):344-354. doi: 10.37349/etat.2023.00138. Epub 2023 Apr 28.
Oncologic emergencies are a wide spectrum of oncologic conditions caused directly by malignancies or their treatment. Oncologic emergencies may be classified according to the underlying physiopathology in metabolic, hematologic, and structural conditions. In the latter, radiologists have a pivotal role, through an accurate diagnosis useful to provide optimal patient care. Structural conditions may involve the central nervous system, thorax, or abdomen, and emergency radiologists have to know the characteristics imaging findings of each one of them. The number of oncologic emergencies is growing due to the increased incidence of malignancies in the general population and also to the improved survival of these patients thanks to the advances in cancer treatment. Artificial intelligence (AI) could be a solution to assist emergency radiologists with this rapidly increasing workload. To our knowledge, AI applications in the setting of the oncologic emergency are mostly underexplored, probably due to the relatively low number of oncologic emergencies and the difficulty in training algorithms. However, cancer emergencies are defined by the cause and not by a specific pattern of radiological symptoms and signs. Therefore, it can be expected that AI algorithms developed for the detection of these emergencies in the non-oncological field can be transferred to the clinical setting of oncologic emergency. In this review, a craniocaudal approach was followed and central nervous system, thoracic, and abdominal oncologic emergencies have been addressed regarding the AI applications reported in literature. Among the central nervous system emergencies, AI applications have been reported for brain herniation and spinal cord compression. In the thoracic district the addressed emergencies were pulmonary embolism, cardiac tamponade and pneumothorax. Pneumothorax was the most frequently described application for AI, to improve sensibility and to reduce the time-to-diagnosis. Finally, regarding abdominal emergencies, AI applications for abdominal hemorrhage, intestinal obstruction, intestinal perforation, and intestinal intussusception have been described.
肿瘤急症是由恶性肿瘤本身或其治疗直接引起的一系列广泛的肿瘤疾病。肿瘤急症可根据潜在的生理病理学分为代谢性、血液学和结构性疾病。在结构性疾病中,放射科医生通过准确诊断发挥关键作用,这有助于为患者提供最佳治疗。结构性疾病可能累及中枢神经系统、胸部或腹部,急诊放射科医生必须了解其中每一种疾病的特征性影像学表现。由于普通人群中恶性肿瘤发病率的增加,以及癌症治疗进展使这些患者的生存率提高,肿瘤急症的数量正在不断增加。人工智能(AI)可能是一种解决方案,可帮助急诊放射科医生应对这一迅速增加的工作量。据我们所知,AI在肿瘤急症领域的应用大多尚未得到充分探索,这可能是由于肿瘤急症的数量相对较少以及训练算法存在困难。然而,癌症急症是由病因定义的,而非特定的放射学症状和体征模式。因此,可以预期,为非肿瘤领域中这些急症的检测而开发的AI算法可应用于肿瘤急症的临床环境。在本综述中,我们采用了从头到尾的方法,探讨了文献报道的有关中枢神经系统、胸部和腹部肿瘤急症的AI应用。在中枢神经系统急症方面,已有关于脑疝和脊髓压迫的AI应用报道。在胸部,涉及的急症有肺栓塞、心脏压塞和气胸。气胸是AI最常描述的应用领域,用于提高敏感性和缩短诊断时间。最后,在腹部急症方面,已描述了AI在腹部出血、肠梗阻、肠穿孔和肠套叠中的应用。