Burtsev E M, Kokoshnikova A N, Zakhovaiko A A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(1):36-9.
The authors conducted a study of tolerance to glucose with the aid of a prednisolone-glucose-tolerance test in 2 groups of patients with brain strokes. The first group consisted of 63 patients younger than 45 years, the second-of 5 cases-older than 55 years of age. In both groups a positive prednisolone-glucose-tolerance test was found in patients with atherosclerosis or hypertensive disease and was not ever seen in strokes of other etiology (rheumatism, nonspecific vasculitis, cerebral vascular aneurysms, blood diseases, etc.). Irrespective of the age, latent diabetus was somewhat more frequently depicted in severe, generalized forms of atherosclerosis. The authors are of the opinion that larvated abnormalities of the carbohydrate metabolism are one of the significant "risk" factors facilitating earlier onset of atherosclerosis and hypertensive disease, as well as their different complications, including cerebral stokes. The report contains facts according to which dysglycemia seen in older patients should be considered not as a physiological aging sysmptoms, but as a sign of latent diabetus.
作者借助泼尼松龙葡萄糖耐量试验，对两组脑卒中患者的葡萄糖耐受性进行了研究。第一组由63名年龄小于45岁的患者组成，第二组由5名年龄大于55岁的患者组成。在两组中，动脉粥样硬化或高血压疾病患者的泼尼松龙葡萄糖耐量试验呈阳性，而其他病因（风湿、非特异性血管炎、脑血管动脉瘤、血液疾病等）的脑卒中患者则从未出现这种情况。无论年龄大小，隐匿性糖尿病在严重的全身性动脉粥样硬化形式中出现的频率略高。作者认为，碳水化合物代谢的隐匿性异常是促使动脉粥样硬化和高血压疾病更早发生及其不同并发症（包括脑卒）的重要“风险”因素之一。该报告包含的事实表明，老年患者中出现的血糖异常不应被视为生理性衰老症状，而应被视为隐匿性糖尿病的迹象。
